CD19 Protein (AA 20-291) (His tag,FITC)
Quick Overview for CD19 Protein (AA 20-291) (His tag,FITC) (ABIN7274067)
Target
See all CD19 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 20-291
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Purification tag / Conjugate
- This CD19 protein is labelled with His tag,FITC.
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Purpose
- FITC-Compatible Human CD19 Protein
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Sequence
- Pro20-Lys291
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Characteristics
- FITC-Compatible Human CD19 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro20-Lys291.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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CD19 Molecule (CD19) (AA 20-291) (Active) protein (His tag)
CD19 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by reduced SDS-PAGE. Active
CD19 Molecule (CD19) (AA 20-291) (Active) protein (Fc Tag)CD19 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD19 Molecule (CD19) (AA 20-291) (Active) protein (Fc Tag,Biotin)CD19 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
CD19 Molecule (CD19) (AA 21-291) protein (His tag)CD19 Origin: Rhesus Monkey, Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD19 Molecule (CD19) (AA 20-291) protein (His tag)CD19 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD19 Molecule (CD19) (AA 20-291) protein (Fc-His Tag)CD19 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD19 Molecule (CD19) (AA 20-291) (Active) protein (His tag,AVI tag,Biotin)CD19 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD19 Molecule (CD19) (AA 19-287) protein (His tag)CD19 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
CD19 Molecule (CD19) protein (Fc Tag)CD19 Origin: Rhesus Monkey Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
CD19 Molecule (CD19) (AA 98-187) protein (GST tag)CD19 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- CD19 (CD19 Molecule (CD19))
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Alternative Name
- CD19
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Background
- CD19 is a B-lineage-specific transmembrane glycoprotein, the expression of which is maintained on more than 95 % B-cell malignancies. This strict lineage restriction makes CD19 an ideal target for immune therapies using chimeric antigen receptors (CARs). T cells engineered to express a chimeric antigen receptor (CAR) against CD19 have recently been FDA approved for the treatment of relapsed or refractory large B-cell lymphoma. Despite the success and curative potential of CD19 CAR T cells, several reports describing disease relapse due to antigen loss are now emerging.
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Molecular Weight
- 60.1 kDa. Due to glycosylation, the protein migrates to 68-72 kDa based on Tris-Bis PAGE result.
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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