CD24 Protein (AA 27-59) (Llama Fc Tag)

Catalog No. ABIN7274119

This Recombinant CD24 protein is expressed in HEK-293 Cells.

Quick Overview for CD24 Protein (AA 27-59) (Llama Fc Tag) (ABIN7274119)

Target: CD24 (CD24 Molecule (CD24))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by Tris-Bis PAGE,> 94 % as determined by HPLC

Product Details

Protein Characteristics: AA 27-59

Purification tag / Conjugate: This CD24 protein is labelled with Llama Fc Tag.

Purpose: Human CD24 Protein

Sequence: Ser27-Gly59

Characteristics: Recombinant Human CD24 Protein is expressed from HEK293 with Llama Fc tag at the C-Terminus.It contains Ser27-Gly59.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CD24 at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CD24 Antibody, hFc Tag with the EC50 of 0.13μg/ml determined by ELISA. See testing image for detail.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: CD24 (CD24 Molecule (CD24))

Alternative Name: CD24

Background: CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers.

Molecular Weight: 30.4 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Tris-Bis PAGE result.

UniProt: P25063

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation