Desmoglein 2 Protein (DSG2) (AA 55-618) (His tag)
Quick Overview for Desmoglein 2 Protein (DSG2) (AA 55-618) (His tag) (ABIN7274502)
Target
See all Desmoglein 2 (DSG2) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 55-618
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Purification tag / Conjugate
- This Desmoglein 2 protein is labelled with His tag.
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Purpose
- Mouse DSG-2/Desmoglein-2 Protein
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Sequence
- Ala55-Ala618
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Characteristics
- Recombinant Mouse DSG-2/Desmoglein-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala55-Ala618.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Desmoglein 2 (DSG2) (AA 50-609) protein (His tag)
DSG2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Desmoglein 2 (DSG2) (AA 24-609) protein (His tag)DSG2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- Desmoglein 2 (DSG2)
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Alternative Name
- DSG-2
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Background
- Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.
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Molecular Weight
- 63.7 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result.
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UniProt
- O55111
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Pathways
- Cell-Cell Junction Organization
Target
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