ECSCR Protein (AA 19-130) (Fc Tag)

Catalog No. ABIN7274508

Product Details

Target: ECSCR (Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR))

Protein Type: Recombinant

Protein Characteristics: AA 19-130

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This ECSCR protein is labelled with Fc Tag.

Purpose: Mouse ECSCR Protein

Sequence: Gln19-Thr130

Characteristics: Recombinant Mouse ECSCR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln19-Thr130.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM Tris,150 mM NaCl ( pH 8.2). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: ECSCR (Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR))

Alternative Name: ECSCR (ECSCR Products)

Synonyms: ARIA Protein, ECSM2 Protein, 1110006O17Rik Protein, endothelial cell surface expressed chemotaxis and apoptosis regulator Protein, ECSCR Protein, Ecscr Protein

Background: Endothelial cell-specific chemotaxis receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles in endothelial cell migration and signal transduction. Zebrafish ecscr is expressed in angioblasts and in axial vessels during angioblast migration and vasculogenesis. Morpholino-directed ecscr knockdown resulted in defective angioblast migration in the posterior lateral plate mesoderm, a process known to depend on vascular endothelial-derived growth factor (VEGF).

Molecular Weight: 38.6 kDa. Due to glycosylation, the protein migrates to 48-68 kDa based on Tris-Bis PAGE result.