EPH Receptor A3 Protein (EPHA3) (AA 21-541) (His tag)
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- Target See all EPH Receptor A3 (EPHA3) Proteins
- EPH Receptor A3 (EPHA3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-541
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EPH Receptor A3 protein is labelled with His tag.
- Purpose
- Mouse EPHA3 Protein
- Sequence
- Glu21-His541
- Characteristics
- Recombinant Mouse EPHA3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-His541.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product EPHA3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- EPH Receptor A3 (EPHA3)
- Alternative Name
- EPHA3 (EPHA3 Products)
- Background
- Erythropoietin-producing hepatocellular carcinoma cell surface type-A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (-295~-261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.
- Molecular Weight
- 59.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_034270
- Pathways
- RTK Signaling, Regulation of Cell Size
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