EPH Receptor B3 Protein (EPHB3) (AA 30-554) (His tag)
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- Target See all EPH Receptor B3 (EPHB3) Proteins
- EPH Receptor B3 (EPHB3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-554
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EPH Receptor B3 protein is labelled with His tag.
- Purpose
- Mouse EphB3 Protein
- Sequence
- Leu30-Leu554
- Characteristics
- Recombinant Mouse EphB3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu30-Leu554.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product EPHB3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- EPH Receptor B3 (EPHB3)
- Alternative Name
- EphB3 (EPHB3 Products)
- Background
- Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is contributed to downregulation of EphB3 in CRC. EphB3 expression in tumor cells may be a useful prognostic indicator for patients with CRC.
- Molecular Weight
- 58.4 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
- UniProt
- P54754
- Pathways
- RTK Signaling
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