FAP Protein (AA 26-760) (His-Avi Tag,Biotin)
Quick Overview for FAP Protein (AA 26-760) (His-Avi Tag,Biotin) (ABIN7274582)
Target
See all FAP ProteinsProtein Type
Origin
Source
Purity
-
-
Protein Characteristics
- AA 26-760
-
Purification tag / Conjugate
- This FAP protein is labelled with His-Avi Tag,Biotin.
-
Purpose
- Biotinylated Cynomolgus FAP Protein
-
Sequence
- Leu26-Asp760
-
Characteristics
- Recombinant Biotinylated Cynomolgus FAP Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Leu26-Asp760.
-
Sterility
- 0.22 μm filtered
-
Endotoxin Level
- Less than 1EU per μg by the LAL method.
-
Biological Activity Comment
- Immobilized Anti-FAP Antibody, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Cynomolgus FAP, His Tag with the EC50 of 58.5ng/ml determined by ELISA. See testing image for detail.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 200 mM Arginine ( pH 8.2).
-
Storage
- -80 °C
-
Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
-
Expiry Date
- 12 months
-
-
- FAP (Fibroblast Activation Protein, alpha (FAP))
-
Alternative Name
- FAP
-
Background
- Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells.
-
Molecular Weight
- 88 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
-
NCBI Accession
- XP_005573377
-
Pathways
- Tube Formation
Target
-