GAS6 Protein (AA 31-637) (His tag)
-
- Target See all GAS6 Proteins
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-637
-
Origin
- Cynomolgus
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GAS6 protein is labelled with His tag.
- Purpose
- Cynomolgus GAS6 Protein
- Sequence
- Ala31-Ala637
- Characteristics
- Recombinant Cynomolgus GAS6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala31-Ala637.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus GAS6, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-Gas6 Antibody, hFc Tag with the EC50 of 36.2ng/ml determined by ELISA. The affinity constant of 1.70 nM as determined in SPR assay (Biacore T200). See testing image for detail.
-
Growth Arrest-Specific 6 (GAS6) (AA 49-678) protein (His tag)
GAS6 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Arrest-Specific 6 (GAS6) (Active) protein (His tag)GAS6 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Growth Arrest-Specific 6 (GAS6) (AA 1-678) protein (GST tag)GAS6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Arrest-Specific 6 (GAS6) (AA 579-678) protein (GST tag)GAS6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Arrest-Specific 6 (GAS6) (AA 31-721) protein (His tag)Crystallography grade GAS6 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Growth Arrest-Specific 6 (GAS6) (AA 28-674) protein (His tag)Crystallography grade GAS6 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Growth Arrest-Specific 6 (GAS6) (AA 136-311) (Active) protein (His tag)GAS6 Origin: Human Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- Alternative Name
- GAS6 (GAS6 Products)
- Synonyms
- fj34a12 Protein, zgc:63860 Protein, wu:fj34a12 Protein, MGC68463 Protein, gas6 Protein, MGC83872 Protein, GAS6 Protein, Gas-6 Protein, AXLLG Protein, AXSF Protein, growth arrest specific 6 Protein, growth arrest-specific 6 Protein, growth arrest specific 6 L homeolog Protein, growth arrest specific 6 S homeolog Protein, GAS6 Protein, gas6 Protein, gas6.L Protein, gas6.S Protein, Gas6 Protein
- Background
- Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).
- Molecular Weight
- 68.55 kDa. Due to glycosylation, the protein migrates to 69-74 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5VGX7
- Pathways
- RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
-
