TNFRSF18 Protein (AA 22-153) (His tag)
Quick Overview for TNFRSF18 Protein (AA 22-153) (His tag) (ABIN7274789)
Target
See all TNFRSF18 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
-
-
Protein Characteristics
- AA 22-153
-
Purification tag / Conjugate
- This TNFRSF18 protein is labelled with His tag.
-
Purpose
- Mouse GITR/TNFRSF18 Protein
-
Sequence
- Ser22-His153
-
Characteristics
- Recombinant Mouse GITR/TNFRSF18 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser22-His153.
-
Sterility
- 0.22 μm filtered
-
Endotoxin Level
- Less than 1 EU per μg by the LAL method.
-
Biological Activity Comment
- Mouse GITR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-161) (Active) protein (His tag)
TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 20-156) (Active) protein (His tag)TNFRSF18 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-161) (Active) protein (Biotin,His-Avi Tag)TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-162) protein (His tag,mFc Tag)TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-162) protein (His tag,Fc Tag)TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 1-241) protein (GST tag)TNFRSF18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-115) protein (GST tag)TNFRSF18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-162) protein (hIgG-His-tag)TNFRSF18 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % SDS
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (Active) protein (His tag,Fc Tag)TNFRSF18 Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by SDS-PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) protein (Fc Tag)TNFRSF18 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
-
Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
-
Expiry Date
- 12 months
-
-
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
-
Alternative Name
- GITR
-
Background
- GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
-
Molecular Weight
- 15.2 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
-
UniProt
- Q8C4K3
-
Pathways
- Cancer Immune Checkpoints
Target
-
