IL18R1 Protein (AA 20-326) (His tag)

Catalog No. ABIN7274982

Product Details

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Protein Type: Recombinant

Protein Characteristics: AA 20-326

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This IL18R1 protein is labelled with His tag.

Purpose: Mouse IL-18 R1/CD218a Protein

Sequence: Lys20-Gly326

Characteristics: Recombinant Mouse IL-18 R1/CD218a Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys20-Gly326.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Alternative Name: IL-18 R1 (IL18R1 Products)

Synonyms: CD218a Protein, CDw218a Protein, IL-1Rrp Protein, IL18RA Protein, IL1RRP Protein, IL-1R9 Protein, IL1R9 Protein, IL1RAPL-2 Protein, TIGIRR-1 Protein, Il18ralpha Protein, Il1rrp Protein, IL-18Ra Protein, IL18R1 Protein, interleukin 18 receptor 1 Protein, interleukin 1 receptor accessory protein like 2 Protein, IL18R1 Protein, IL1RAPL2 Protein, Il18r1 Protein

Background: Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naive T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.

Molecular Weight: 36.5 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Tris-Bis PAGE result.

UniProt: Q61098