Leptin Receptor Protein (LEPR) (AA 22-839) (His tag)

Catalog No. ABIN7275141

Product Details

Target: Leptin Receptor (LEPR)

Protein Type: Recombinant

Protein Characteristics: AA 22-839

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Leptin Receptor protein is labelled with His tag.

Purpose: Human LEPR Protein

Sequence: Phe22-Asp839

Characteristics: Recombinant Human LEPR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe22-Asp839.

Purity: > 95 % as determined by Tris-Bis PAGE

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Leptin Receptor (LEPR)

Alternative Name: LEPR (LEPR Products)

Synonyms: CD295 Protein, LEP-R Protein, LEPRD Protein, OB-R Protein, OBR Protein, obr Protein, cd295 Protein, ob-rb Protein, Fa Protein, LEPROT Protein, Leprb Protein, Modb1 Protein, OB-RGRP Protein, Obr Protein, db Protein, diabetes Protein, obese-like Protein, obl Protein, ObRb Protein, Ob-R Protein, Ob-RM Protein, lepr Protein, leptin receptor Protein, leptin receptor S homeolog Protein, LEPR Protein, lepr Protein, Lepr Protein, lepr.S Protein

Background: Leptin receptor is a fundamental regulator in physiological functions of the regulation of food intake, energy homeostasis, immune function, and reproduction as well as on ovarian follicular cells on the placenta and lactating mammary glands.

Molecular Weight: 94.59 kDa. Due to glycosylation, the protein migrates to 120-150 kDa based on Tris-Bis PAGE result.

Pathways: JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour