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MERTK Protein (AA 19-497) (His tag)

MERTK Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275244
  • Target See all MERTK Proteins
    MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 19-497
    Origin
    • 22
    • 7
    • 3
    • 1
    • 1
    Mouse
    Source
    • 12
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MERTK protein is labelled with His tag.
    Purpose
    Mouse MERTK/Mer Protein
    Sequence
    Gly19-Met497
    Characteristics
    Recombinant Mouse MERTK/Mer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly19-Met497.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
    Alternative Name
    MERTK (MERTK Products)
    Synonyms
    MER Protein, RP38 Protein, c-mer Protein, Eyk Protein, Mer Protein, Nyk Protein, nmf12 Protein, rdy Protein, C-EYK Protein, MERTK Protein, DKFZp469D2215 Protein, si:ch1073-268l12.2 Protein, MER proto-oncogene, tyrosine kinase Protein, c-mer proto-oncogene tyrosine kinase Protein, c-mer proto-oncogene tyrosine kinase a Protein, MERTK Protein, Mertk Protein, mertka Protein
    Background
    MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans.
    Molecular Weight
    53.38 kDa. Due to glycosylation, the protein migrates to 85-105 kDa based on Tris-Bis PAGE result.
    UniProt
    Q60805
    Pathways
    RTK Signaling
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