MARCO Protein (AA 405-520) (His tag)
-
- Target See all MARCO Proteins
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 405-520
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MARCO protein is labelled with His tag.
- Purpose
- Human MARCO Protein
- Sequence
- Ser405-Val520
- Characteristics
- Recombinant Human MARCO Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ser405-Val520.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product MARCO Protein
-
Macrophage Receptor with Collagenous Structure (MARCO) (AA 70-518) protein (His tag)
MARCO Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Macrophage Receptor with Collagenous Structure (MARCO) (AA 65-520) protein (His tag)Crystallography grade MARCO Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Macrophage Receptor with Collagenous Structure (MARCO) (AA 70-518) protein (His tag)Crystallography grade MARCO Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Macrophage Receptor with Collagenous Structure (MARCO) (AA 1-520) protein (Strep Tag)Crystallography grade MARCO Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Macrophage Receptor with Collagenous Structure (MARCO) (AA 1-518) protein (Strep Tag)Crystallography grade MARCO Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS, 200 mM L-arginine ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- Alternative Name
- MARCO (MARCO Products)
- Synonyms
- AI323439 Protein, Ly112 Protein, Scara2 Protein, SCARA2 Protein, macrophage receptor with collagenous structure Protein, MARCO Protein, Marco Protein
- Background
- Macrophage receptor with collagenous structure (MARCO) is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). MARCO contributes to normal cholesterol uptake in macrophages, therefore, in the absence of MARCO, macrophages are more susceptible to a greater inflammatory response by particulates known to cause NLRP3 inflammasome activation and the effect is due to increased LMP.
- Molecular Weight
- 13.8 kDa. Due to glycosylation, the protein migrates to 14-20 kDa based on Tris-Bis PAGE result.
- Pathways
- Activation of Innate immune Response
-
