Neuropilin 1 Protein (NRP1) (AA 22-644) (His tag)
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- Target See all Neuropilin 1 (NRP1) Proteins
- Neuropilin 1 (NRP1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-644
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Neuropilin 1 protein is labelled with His tag.
- Purpose
- Human Neuropilin-1 Protein
- Sequence
- Phe22-Lys644
- Characteristics
- Recombinant Human Neuropilin-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe22-Lys644.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human VEGF165, No Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human Neuropilin-1, His Tag with the EC50 of 2.0μg/ml determined by ELISA. See testing image for detail.
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Neuropilin 1 (NRP1) (AA 22-644) protein (His tag)
NRP1 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Neuropilin 1 (NRP1) (AA 22-644) (Active) protein (Fc Tag)NRP1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Neuropilin 1 (NRP1) (AA 23-644) protein (GST tag)NRP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neuropilin 1 (NRP1) (AA 22-131) protein (GST tag)NRP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neuropilin 1 (NRP1) (AA 22-856) protein (His tag)Crystallography grade NRP1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Neuropilin 1 (NRP1) (AA 22-856) protein (His tag)Crystallography grade NRP1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Neuropilin 1 (NRP1) (AA 22-923) protein (rho-1D4 tag)Crystallography grade NRP1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Neuropilin 1 (NRP1) (AA 22-923) protein (rho-1D4 tag)Crystallography grade NRP1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Neuropilin 1 (NRP1) (AA 22-644) (Active) protein (His tag)NRP1 Origin: Human Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. Active
Neuropilin 1 (NRP1) (AA 22-856) (Active) protein (His tag)NRP1 Origin: Mouse Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Neuropilin 1 (NRP1)
- Alternative Name
- Neuropilin-1 (NRP1 Products)
- Synonyms
- NRP1 Protein, cd304 Protein, neuropilin Protein, np-1 Protein, npn-1 Protein, nrp Protein, nrp-1 Protein, vegf165r Protein, BDCA4 Protein, CD304 Protein, NP1 Protein, NRP Protein, VEGF165R Protein, C530029I03 Protein, NP-1 Protein, NPN-1 Protein, Npn1 Protein, Nrp Protein, neuropilin 1 Protein, neuropilin 1 L homeolog Protein, NRP1 Protein, nrp1 Protein, Nrp1 Protein, nrp1.L Protein
- Background
- Neuropilin 1 (NRP1) is a transmembrane glycoprotein that acts as a co-receptor for a number of extracellular ligands including class III/IV semaphorins, certain isoforms of vascular endothelial growth factor and transforming growth factor beta.
- Molecular Weight
- 70.97 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_001019799
- Pathways
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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