PGLYRP1 Protein (AA 22-196) (Fc Tag)
Quick Overview for PGLYRP1 Protein (AA 22-196) (Fc Tag) (ABIN7275449)
Target
See all PGLYRP1 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 22-196
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Purification tag / Conjugate
- This PGLYRP1 protein is labelled with Fc Tag.
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Purpose
- Human PGLYRP1 Protein
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Sequence
- Gln22-Pro196
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Characteristics
- Recombinant Human PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-Pro196.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
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Alternative Name
- PGLYRP1
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Background
- Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.
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Molecular Weight
- 46.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
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UniProt
- O75594
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Pathways
- Activation of Innate immune Response
Target
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