PGLYRP1 Protein (AA 19-182) (Fc Tag)

Catalog No. ABIN7275450

This Recombinant PGLYRP1 protein is produced in HEK-293 Cells.

Quick Overview for PGLYRP1 Protein (AA 19-182) (Fc Tag) (ABIN7275450)

Target: PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by Tris-Bis PAGE

Product Details

Protein Characteristics: AA 19-182

Purification tag / Conjugate: This PGLYRP1 protein is labelled with Fc Tag.

Purpose: Mouse PGLYRP1 Protein

Sequence: Phe19-Glu182

Characteristics: Recombinant Mouse PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe19-Glu182.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS, 10 % Glycerol ( pH 8.0).

Storage: -80 °C

Storage Comment: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))

Alternative Name: PGLYRP1

Background: Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.

Molecular Weight: 45.7 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result.

UniProt: O88593

Pathways: Activation of Innate immune Response