SIRPB1 Protein (AA 30-371, Isoform 3) (His-Avi Tag)
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- Target See all SIRPB1 Proteins
- SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-371, Isoform 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SIRPB1 protein is labelled with His-Avi Tag.
- Purpose
- Human SIRP Beta 1 isoform 3 Protein
- Sequence
- Glu30-Leu371
- Characteristics
- Recombinant Human SIRP Beta 1 isoform 3 Proteinis expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Leu371.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-371), (Isoform 3) protein (His-Avi Tag,Biotin)
SIRPB1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Signal-Regulatory Protein beta 1 (SIRPB1) (AA 1-181) protein (GST tag)SIRPB1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-371) protein (His tag)Crystallography grade SIRPB1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-398) protein (rho-1D4 tag)Crystallography grade SIRPB1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Signal-Regulatory Protein beta 1 (SIRPB1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SIRPB1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
- Alternative Name
- SIRP Beta 1 (SIRPB1 Products)
- Synonyms
- CD172b Protein, SIRP-BETA-1 Protein, SIRPB1 Protein, SIRPG Protein, signal regulatory protein beta 1 Protein, signal-regulatory protein beta-1 Protein, signal-regulatory protein beta-1 isoform 3 Protein, SIRPB1 Protein, LOC458036 Protein, LOC458430 Protein, LOC485809 Protein, LOC715912 Protein, LOC100458151 Protein
- Background
- Signal regulatory protein β1 (SIRPB1) is a signal regulatory protein member of the immunoglobulin superfamily and is capable of modulating receptor tyrosine kinase-coupled signaling. Copy number variations at the SIRPB1 locus were previously reported to associate with prostate cancer aggressiveness in patients.SIRPB1 gene amplification and overexpression were detected in prostate cancer specimens. The knockdown of SIRPB1 significantly suppressed cell growth in colony formation assays and cell mobility.
- Molecular Weight
- 39.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
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