Desmoglein 2 Protein (DSG2) (AA 24-609) (His tag)

Catalog No. ABIN7491501

Recombinant Desmoglein 2 protein expressed in HEK-293 Cells.

Quick Overview for Desmoglein 2 Protein (DSG2) (AA 24-609) (His tag) (ABIN7491501)

Target: Desmoglein 2 (DSG2)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 24-609

Purification tag / Conjugate: This Desmoglein 2 protein is labelled with His tag.

Purpose: Recombinant Human DSG2(24-609) Protein with C-terminal 6xHis tag

Specificity: DSG2 (Leu24-Gly609) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: Desmoglein 2 (DSG2)

Alternative Name: DSG2

Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]

Molecular Weight: predicted molecular mass of 66.4 kDa after removal of the signal peptide. The apparent molecular mass of DSG2(24-609)-His is 70-100 kDa due to glycosylation.

UniProt: Q14126

Pathways: Cell-Cell Junction Organization