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XIAP Protein (AA 1-497) (His tag)

XIAP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505227
  • Target See all XIAP Proteins
    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-497
    Origin
    • 7
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This XIAP protein is labelled with His tag.
    Sequence
    Met 1-Ser 497
    Characteristics
    A DNA sequence encoding the Human XIAP protein (P98170) (Met 1-Ser 497) was expressed with a N-His&C-His tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
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    Discover our top product XIAP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
    Alternative Name
    XIAP (XIAP Products)
    Background

    Abbreviation: XIAP

    Target Synonym: E3 ubiquitin-protein ligase XIAP,XIAP,Baculoviral IAP repeat-containing protein 4,IAP-like protein,Inhibitor of apoptosis protein 3,RING-type E3 ubiquitin transferase XIAP,X-linked inhibitor of apoptosis protein

    Background: XIAP (X-chromosome linked inhibitor of apoptosis) is a member of the apoptosis (IAP) family of proteins that inhibit caspases. The BIR2 domain of XIAP inhibits caspase-3 and caspase-7. The ability of XIAP to inhibit caspases is prevented by SMAC/Diablo through binding to XIAP-BIR2 and -BIR3 domains.

    Molecular Weight

    Calculated MW: 54.56 kDa

    Observed MW: 54 kDa

    UniProt
    P98170
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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