XIAP Protein (AA 1-497) (His tag)
-
- Target See all XIAP Proteins
- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-497
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This XIAP protein is labelled with His tag.
- Sequence
- Met 1-Ser 497
- Characteristics
- A DNA sequence encoding the Human XIAP protein (P98170) (Met 1-Ser 497) was expressed with a N-His&C-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product XIAP Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
-
- Target
- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
- Alternative Name
- XIAP (XIAP Products)
- Background
-
Abbreviation: XIAP
Target Synonym: E3 ubiquitin-protein ligase XIAP,XIAP,Baculoviral IAP repeat-containing protein 4,IAP-like protein,Inhibitor of apoptosis protein 3,RING-type E3 ubiquitin transferase XIAP,X-linked inhibitor of apoptosis protein
Background: XIAP (X-chromosome linked inhibitor of apoptosis) is a member of the apoptosis (IAP) family of proteins that inhibit caspases. The BIR2 domain of XIAP inhibits caspase-3 and caspase-7. The ability of XIAP to inhibit caspases is prevented by SMAC/Diablo through binding to XIAP-BIR2 and -BIR3 domains.
- Molecular Weight
-
Calculated MW: 54.56 kDa
Observed MW: 54 kDa
- UniProt
- P98170
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
-