SLC7A14 Protein (AA 1-771) (His tag)

Catalog No. ABIN7555316

This Recombinant SLC7A14 protein is expressed in HEK-293 Cells.

Quick Overview for SLC7A14 Protein (AA 1-771) (His tag) (ABIN7555316)

Target: SLC7A14 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 14 (SLC7A14))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-771

Purification tag / Conjugate: This SLC7A14 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant SLC7A14 Protein expressed in mammalian cells.

Sequence: MSGFFTSLDP RRVQWGAAWY AMHSRILRTK PVESMLEGTG TTTAHGTKLA QVLTTVDLIS LGVGSCVGTG MYVVSGLVAK EMAGPGVIVS FIIAAVASIL SGVCYAEFGV RVPKTTGSAY TYSYVTVGEF VAFFIGWNLI LEYLIGTAAG ASALSSMFDS LANHTISRWM ADSVGTLNGL GKGEESYPDL LALLIAVIVT IIVALGVKNS IGFNNVLNVL NLAVWVFIMI AGLFFINGKY WAEGQFLPHG WSGVLQGAAT CFYAFIGFDI IATTGEEAKN PNTSIPYAIT ASLVICLTAY VSVSVILTLM VPYYTIDTES PLMEMFVAHG FYAAKFVVAI GSVAGLTVSL LGSLFPMPRV IYAMAGDGLL FRFLAHVSSY TETPVVACIV SGFLAALLAL LVSLRDLIEM MSIGTLLAYT LVSVCVLLLR YQPESDIDGF VKFLSEEHTK KKEGILADCE KEACSPVSEG DEFSGPATNT CGAKNLPSLG DNEMLIGKSD KSTYNVNHPN YGTVDMTTGI EADESENIYL IKLKKLIGPH YYTMRIRLGL PGKMDRPTAA TGHTVTICVL LLFILMFIFC SFIIFGSDYI SEQSWWAILL VVLMVLLIST LVFVILQQPE NPKKLPYMAP CLPFVPAFAM LVNIYLMLKL STITWIRFAV WCFVGLLIYF GYGIWNSTLE ISAREEALHQ STYQRYDVDD PFSVEEGFSY ATEGESQEDW GGPTEDKGFY YQQMSDAKAN GRTSSKAKSK SKHKQNSEAL IANDELDYSP E Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SLC7A14 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 14 (SLC7A14))

Alternative Name: SLC7A14

Background: Solute carrier family 7 member 14 (Gamma-aminobutyric acid transporter SLC7A14),FUNCTION: Imports 4-aminobutanoate (GABA) into lysosomes. May act as a GABA sensor that regulates mTORC2-dependent INS signaling and gluconeogenesis. The transport mechanism and substrate selectivity remain to be elucidated. {ECO:0000250|UniProtKB:Q8BXR1}.

Molecular Weight: 84.1 kDa

UniProt: Q8TBB6

AlphaFold: Q8TBB6