ZHX3 Protein (AA 1-956) (His tag)

Catalog No. ABIN7556114

This Recombinant ZHX3 protein is expressed in HEK-293 Cells.

Quick Overview for ZHX3 Protein (AA 1-956) (His tag) (ABIN7556114)

Target: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-956

Purification tag / Conjugate: This ZHX3 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant ZHX3 Protein expressed in mammalian cells.

Sequence: MASKRKSTTP CMIPVKTVVL QDASMEAQPA ETLPEGPQQD LPPEASAASS EAAQNPSSTD GSTLANGHRS TLDGYLYSCK YCDFRSHDMT QFVGHMNSEH TDFNKDPTFV CSGCSFLAKT PEGLSLHNAT CHSGEASFVW NVAKPDNHVV VEQSIPESTS TPDLAGEPSA EGADGQAEII ITKTPIMKIM KGKAEAKKIH TLKENVPSQP VGEALPKLST GEMEVREGDH SFINGAVPVS QASASSAKNP HAANGPLIGT VPVLPAGIAQ FLSLQQQPPV HAQHHVHQPL PTAKALPKVM IPLSSIPTYN AAMDSNSFLK NSFHKFPYPT KAELCYLTVV TKYPEEQLKI WFTAQRLKQG ISWSPEEIED ARKKMFNTVI QSVPQPTITV LNTPLVASAG NVQHLIQAAL PGHVVGQPEG TGGGLLVTQP LMANGLQATS SPLPLTVTSV PKQPGVAPIN TVCSNTTSAV KVVNAAQSLL TACPSITSQA FLDASIYKNK KSHEQLSALK GSFCRNQFPG QSEVEHLTKV TGLSTREVRK WFSDRRYHCR NLKGSRAMIP GDHSSIIIDS VPEVSFSPSS KVPEVTCIPT TATLATHPSA KRQSWHQTPD FTPTKYKERA PEQLRALESS FAQNPLPLDE ELDRLRSETK MTRREIDSWF SERRKKVNAE ETKKAEENAS QEEEEAAEDE GGEEDLASEL RVSGENGSLE MPSSHILAER KVSPIKINLK NLRVTEANGR NEIPGLGACD PEDDESNKLA EQLPGKVSCK KTAQQRHLLR QLFVQTQWPS NQDYDSIMAQ TGLPRPEVVR WFGDSRYALK NGQLKWYEDY KRGNFPPGLL VIAPGNRELL QDYYMTHKML YEEDLQNLCD KTQMSSQQVK QWFAEKMGEE TRAVADTGSE DQGPGTGELT AVHKGMGDTY SEVSENSESW EPRVPEASSE PFDTSSPQAG RQLETD Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Alternative Name: ZHX3

Background: Zinc fingers and homeoboxes protein 3 (Triple homeobox protein 1) (Zinc finger and homeodomain protein 3),FUNCTION: Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA. {ECO:0000269|PubMed:12659632, ECO:0000269|PubMed:21174497}.

Molecular Weight: 104.7 kDa

UniProt: Q9H4I2

AlphaFold: Q9H4I2