TFEC Protein (AA 1-317) (His tag)

Catalog No. ABIN7556250

Recombinant TFEC protein expressed in HEK-293 Cells.

Quick Overview for TFEC Protein (AA 1-317) (His tag) (ABIN7556250)

Target: TFEC (Transcription Factor EC (TFEC))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-317

Purification tag / Conjugate: This TFEC protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Tfec Protein expressed in mammalian cells.

Sequence: MTFDCRVCDQ TLKRAQPPAA SCMPLAEHEP MSPDSDAGCA GNPFTNLLAL GKKDGAEKWH LSGSILDVYS DEQGISSANA GLTDAPCPSI LPMRKEIAET DGRALAKERQ KKDNHNLIER RRRYNINYRI KELGTLIPKS NDPDMRWNKG TILKASVDYI KWLQKEQQRA RELEHRQKKL EHANRQLRLR IQELEIQARA HGLPILASLG TADVGTHITK QQTHPERNLG GCCLQLTPTQ GTSPEFYEQA VAFSDPLSHF TDLSFSAALK EEQRLDGMLL SDTICPFGTD PLLSAISPAV SKASSRSSLS SEDGDEL Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TFEC (Transcription Factor EC (TFEC))

Alternative Name: Tfec

Background: Transcription factor EC (TFE-C) (mTFEC),FUNCTION: Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence) (By similarity). Binds to element F in an E-box sequence-specific manner (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form. {ECO:0000250, ECO:0000269|PubMed:11818452}.

Molecular Weight: 35.1 kDa

UniProt: Q9WTW4

AlphaFold: Q9WTW4