SLC22A13 Protein (AA 1-551) (His tag)

Catalog No. ABIN7557903

Recombinant SLC22A13 protein expressed in HEK-293 Cells.

Quick Overview for SLC22A13 Protein (AA 1-551) (His tag) (ABIN7557903)

Target: SLC22A13 (Solute Carrier Family 22 (Organic Anion Transporter), Member 13 (SLC22A13))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-551

Purification tag / Conjugate: This SLC22A13 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Slc22a13 Protein expressed in mammalian cells.

Sequence: MAQFAQVMAE VGDFGRFQVR LTILMGIPNF LAAFFIFGQV FMVLDEAHHC SVSWVKNHTF NLSAAEQLAI SIPNDTAGRP ESCLMFRPPP DSASLEDILS HRFNETQACD SGWDYPENRP QSLKKEFDLV CDRKNLKKTS QSVFMAGLLV GALVFGPVCD WIGRRPSLLM QVLLSGITSM ATAFVSSFEL YLALRFVLAT ANAGFLLSTN VLISEWVGPS WRTQAVVLAQ SNVALGQMVL AGLAYGVRNW RLLQITGTAP VLLLFFYFWV LPESPRWLLS QGRTEEAKQL VQKAALVNGR PLSPELLNQL VPEKTGPSGN ALDLFRHPHL RKVTLILIAV WFVDSLVYYS LSFQVGDFGL DIYVTQLIFG AVEMPGRFLS VLMMEKLGRK WSQLCTLTLA GIMYIIIIFI PGDLPTVVTV LAVVGKFASA AAFTISYVYT AELFPTIIRQ TGMGLVSIFS RVGGIITPLV MLLEQYHQAI PMVIFGSLPI GAGLLCALLP ETRGQTLKDT LQDLEQGLPA GSHKTAPQRQ DMEALGRTSS VRVAVVKSSY F Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SLC22A13 (Solute Carrier Family 22 (Organic Anion Transporter), Member 13 (SLC22A13))

Alternative Name: Slc22a13

Background: Solute carrier family 22 member 13 (Organic anion transporter 10) (OAT10) (Organic cation transporter-like 3) (ORCTL-3),FUNCTION: Anion antiporter that mediates the transport of orotate and nicotinate in exchange for organic or inorganic anions (PubMed:35144162). Translocates orotate across the apical membrane of proximal tubule epithelial cells. Possibly involved in orotate renal reabsorption and nicotinate intestinal reabsorption (PubMed:35144162). Orotate transport is Cl(-)-dependent (By similarity). {ECO:0000250|UniProtKB:Q9Y226, ECO:0000269|PubMed:35144162}.

Molecular Weight: 60.7 kDa

UniProt: Q6A4L0

AlphaFold: Q6A4L0