GPR61 Protein (AA 1-449) (His tag)

Catalog No. ABIN7559062

This Recombinant GPR61 protein is produced in HEK-293 Cells.

Quick Overview for GPR61 Protein (AA 1-449) (His tag) (ABIN7559062)

Target: GPR61 (G Protein-Coupled Receptor 61 (GPR61))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-449

Purification tag / Conjugate: This GPR61 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Gpr61 Protein expressed in mammalian cells.

Sequence: MESSPIPQSS GNSSTLGRAL QTPGPSTASG VPELGLRDVA SESVALFFML LLDLTAVAGN AAVMAVIAKT PALRKFVFVF HLCLVDLLAA LTLMPLAMLS SSALFDHALF GEVACRLYLF LSVCFVSLAI LSVSAINVER YYYVVHPMRY EVRMTLGLVA SVLVGVWVKA LAMASVPVLG RVYWEEGAPS VNPGCSLQWS HSAYCQLFVV VFAVLYFLLP LILIFVVYCS MFRVARVAAM QHGPLPTWME TPRQRSESLS SRSTMVTSSG AHQTTPHRTF GGGKAAVVLL AVGGQFLLCW LPYFSFHLYV ALSAQPISAG QVENVVTWIG YFCFTSNPFF YGCLNRQIRG ELSKQFVCFF KAAPEEELRL PSREGSIEEN FLQFLQGTSE NWVSRPLPSP KREPPPVVDF RIPGQIAEET SEFLEQQLTS DIIMSDSYLR PAPSPRLES Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: GPR61 (G Protein-Coupled Receptor 61 (GPR61))

Alternative Name: Gpr61

Background: G-protein coupled receptor 61,FUNCTION: Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). May be involved in the regulation of food intake and body weight (PubMed:21971119). {ECO:0000250|UniProtKB:Q9BZJ8, ECO:0000269|PubMed:21971119}.

Molecular Weight: 49.4 kDa

UniProt: Q8C010

AlphaFold: Q8C010