Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) (AA 1-570) protein (His tag)

Catalog No. ABIN7559388

Recombinant protein expressed in HEK-293 Cells.

Quick Overview for Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) (AA 1-570) protein (His tag) (ABIN7559388)

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-570

Purification tag / Conjugate: His tag

Purpose: Predefined custom protein recombinant Stau2 Protein expressed in mammalian cells.

Sequence: MANPKEKTPV CLVNELARFH SIQPQYKLLN ESGPAHSKMF SVQLSLGEQT WESEGSSIKK AQQAVANKAL TESTLPKPVQ KPPKSNVNNN PGSITPTVEL NGLAMKRGEP AIYRPLDPKP FPNYRANYNF RGMYNQRYHC PMPKIFYVQL TVGNNEFFGE GKTRQAARHN AAMKALQALQ NEPIPEKSPQ NGESGKEMDD DKDANKSEIS LVFEIALKRN MPVSFEVIKE SGPPHMKSFV TRVSVGEFSA EGEGNSKKLS KKRAATTVLQ ELKKLPPLPV VEKPKLFFKK RPKTIVKAGP DYGQGMNPIS RLAQIQQARK EKEPDYILLS ERGMPRRREF VMQVKVGNEV ATGTGPNKKI AKKNAAEAML LQLGYKASTS LQDPLDKTGE NKGWSGPKPG FPEPTNNTPK GILHLSPDVY QEMEASRHRV TSGTTLSYLS PKDMNQPSSS FFSVSPSSTS SATVARELLM NGTSPTAEAI GLKGSSPTSP CSSVQPSKQL EYLARIQGFQ AALSALKQFS EQGLESIDGA VNVEKGSLEK QAKHLREKAD NNQAKPASIS QDCKKSKSAI Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Alternative Name: Stau2

Background: Double-stranded RNA-binding protein Staufen homolog 2,FUNCTION: RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesis occurs within the dendrite, the localization of specific mRNAs to dendrites may be a prerequisite for neurite outgrowth and plasticity at sites distant from the cell body (By similarity). {ECO:0000250|UniProtKB:Q68SB1}.

Molecular Weight: 62.5 kDa

UniProt: Q8CJ67

AlphaFold: Q8CJ67