TBC1D25 Protein (AA 1-742) (His tag)

Catalog No. ABIN7561853

This Recombinant TBC1D25 protein is expressed in HEK-293 Cells.

Quick Overview for TBC1D25 Protein (AA 1-742) (His tag) (ABIN7561853)

Target: TBC1D25 (TBC1 Domain Family, Member 25 (TBC1D25))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-742

Purification tag / Conjugate: This TBC1D25 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Tbc1d25 Protein expressed in mammalian cells.

Sequence: MRPPAQARWE GQGPTAPLRL RSGARWGRGR PHCWVYVRVR VTIGYHLDRD DSGGMATTSA ASDSACSAAP PPVGGAQAAA AVEEEEREVV RVRVKKCESF LSPEFRSFAV DPQITSLDVL QHILIRAFDL NGKKNFGISY LARDRLGQET FLSLLSDWDL STAFATASKP YLQLRVDIRP SEDSPLLEDW DIISPKDVIG SDVLLAEKRS SLTTAALPFT QSILSQVGRT LSKVQQVLSW SYGEDVKPFK PPLSDAEFHT YLNHEGQLSR PEELRLRIYH GGVEPSLRKV VWRYLLNVYP DGLTGRERMD YMKRKSREYE QLKSEWAQRV NPEDLEFIRS TVLKDVLRTD RAHPYYAGPE DGPHLRALHD LLTTYAVTHP QVSYCQGMSD LASPILAVMD HEGHAFVCFC GIMKRLAANF HPDGRAMATK FAHLKLLLRH ADPDFYQYLQ EAGADDLFFC YRWLLLELKR EFAFDDALRM LEVTWSSLPP DPPEHEVELV GPPSQVADTG FGSHRGRPVR QRHMLRPAGG GGGAFEDAVV HLAASSQGPS GGGRLLRQAS LDGLQQLRDN MGLRKDHLVQ LSHPATLISS KSLSEPLLNS PDPLLSTSSR PDSPSSSSPP STQEASPSGD IAVGSPLMQE VGSPRDPGKP VPPPPPMGLP PPQEFGRGNP FMLFLCLAIL LEHRDHIMRN GLDYNELAMH FDRLVRKHHL GRVLRRAKAL FADYLQSEVW DSEEGAEATA PS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TBC1D25 (TBC1 Domain Family, Member 25 (TBC1D25))

Alternative Name: Tbc1d25

Background: TBC1 domain family member 25,FUNCTION: Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes. {ECO:0000250}.

Molecular Weight: 82.6 kDa

UniProt: A1A5B6

AlphaFold: A1A5B6