CAMSAP1 Protein (AA 1-1581) (His tag)

Catalog No. ABIN7561911

Recombinant CAMSAP1 protein expressed in HEK-293 Cells.

Quick Overview for CAMSAP1 Protein (AA 1-1581) (His tag) (ABIN7561911)

Target: CAMSAP1 (Calmodulin Regulated Spectrin Associated Protein 1 (CAMSAP1))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1581

Purification tag / Conjugate: This CAMSAP1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Camsap1 Protein expressed in mammalian cells.

Sequence: MVDAGGRCAA EGWRRMEAPP EGADLVPLDR YDAARAKIAA NLQWICAKAY GLDNIPEDLR DPFYIDQYEQ EHIKPPVIKL LLSSELYCRV CSLILKGDQV ATLQGHQSVI QALSRKGIYV MESDDTPVTD ADLSQAPIKM SGHMAMVDAL MMAYTVEMIS IEKVVASVKR FSTFSASKEL PYDLEDAMVF WINKVNLKMR EITEKEVKLK QQPLESPAHQ KVRYRREHLS ARQSPYFPLL EDLMRDGSDG AALLAVVHYY CPEQMKLDDI CLKEVPSMAD SLYNIRLLRE FSNEHLNKCF YLTLEDMLYA PLVLKPNVMV FIAELFWWFE NVKPDFVQPR DIQELKDAKT VLQQKSSRPP VPISNATKRS FLGSPAAMSP ADQPPSTQPL AEGSHRYHLH SEEPECLGKG ASTFSPSHPL LPLRQKQQKV SQTEEIPDQR HRSNSLTRVD GQPRGAIGAW PDKKNRPVSQ PTSFALHHAA SCDVDPSSGD SVSLARSISK DSLASNIIHL TPQNQPHPSA GKSNGKSLLS NVNIEDEDEE LVAIIRTDVS PPSPQMPRTS PQAPGLVASI RSPQRQADTL ESKPDSFYLE PLMPAVLRPA KEKQITTKED ERGEGRPRTI MAKRPSEGSQ PMVRKKVSGG HGSRDLNRTF TPIPCSEFAA SIDLAEVGPQ SAEATGEGQP LALGRFDTLP QGQAADGFFL HVGRAEEDEG RWYVGSQSPS SHDSEPWTIL RQDSDSDVVD VEDTEQDFIG EDHPVVIPRY AGEEESAKLQ EDMKVKEHED KDDASGRSSP CLSTTSQLSS MSMASGSVKM TSFAERKLQR LNSCETKSST SSSQKTTPDA SESCPAPLTT WRQKREQSPG RHSKDPASLL ASELVQLHMQ LEEKRRAIEA QKKKMEALSA RQRLKLGKAA FLHVVKKGKA DGAPQPLRPE HFTKEFTQHN GEDLDDGTCK TEGFLVKEEQ RDLSDAQDVA FVQLHKPRDP AALHDGEKHR MISTALLEDS VGEVDVNECD LSIEKLNETI STLQQAILKI SQQQEQLLMK SPTVPTPGTK NNCQDQKIKA PVHFVEPLSP TGVPGHRKPP RLGQGRNSRS GRPAELKVPK DRQQGCSRSK TPTPSVETLP QSRSLPPSTH PRSPSDPGGE LPEKCLFDSY RLHDESNHRT FVLSSCKDAN IVSEQVNFKE GLDTSVKEAG LSSSTITGKE HTPVEEPLRS KASLIEVDLS DLKAPDEDGE VVGHESSVEL GGDSDQKPGV GFFFKDEQKA EDELAKKRAA FLLKQQRKAE EARARKQQLE AEVELKRDEA RRKAEEDRLR KEEEKARREL IKQEYLRRKQ QQALEEQGLG KPKSKPKKPR PKSVHREESY SDSGTKCSST HNLSQTHSGS SLSLASAATT EPESVYSGGT PSHRVESLEA LPILSRNPSR STDRDWETAS AASSLASVAE YTGPKLFKEP SSKSNKPIIH NAISHCCLAG KVNEPHKNSI LELEKCDANH YIILFRDAGC QFRALYCYQP DTEEIYKLTG TGPKSITKKM IDKLYKYSSD RKQFNLIPAK TMSVSVDALT IHNHLWQPKR PTVPKKTQTR K Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: CAMSAP1 (Calmodulin Regulated Spectrin Associated Protein 1 (CAMSAP1))

Alternative Name: Camsap1

Background: Calmodulin-regulated spectrin-associated protein 1,FUNCTION: Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and stabilizes microtubules. Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In contrast to CAMSAP2 and CAMSAP3, tracks along the growing tips of minus-end microtubules without significantly affecting the polymerization rate: binds at the very tip of the microtubules minus-end and acts as a minus-end tracking protein (-TIP) that dissociates from microtubules after allowing tubulin incorporation. Through interaction with spectrin may regulate neurite outgrowth. {ECO:0000250|UniProtKB:Q5T5Y3}.

Molecular Weight: 175.9 kDa

UniProt: A2AHC3

AlphaFold: A2AHC3