RABGGTB Protein (AA 1-339) (His tag)

Catalog No. ABIN7563434

This Recombinant RABGGTB protein is expressed in HEK-293 Cells.

Quick Overview for RABGGTB Protein (AA 1-339) (His tag) (ABIN7563434)

Target: RABGGTB (Rab Geranylgeranyltransferase, beta Subunit (RABGGTB))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-339

Purification tag / Conjugate: This RABGGTB protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Rabggtb Protein expressed in mammalian cells.

Sequence: MGSLLFSWKG TQQKDVTIKS DAPDTLLLEK HADYIASYGS KKDDYEYCMS EYLRMSGVYW GLTVMDLMGQ LHRMNREEIL VFIKSCQHEC GGISASIGHD PHLLYTLSAV QILTLYDSVH VINVDKVVAY VQSLQKEDGS FAGDIWGEID TRFSFCAVAT LALLGKLDAI NVEKAIEFVL SCMNFDGGFG CRPGSESHAG QIYCCTGFLA ITSQLHQVNS DLLGWWLCER QLPSGGLNGR PEKLPDVCYS WWVLASLKII GRLHWIDREK LRSFILACQD EETGGFADRP GDMVDPFHTL FGIAGLSLLG EEQIKPVSPV FCMPEEVLQR VNVQPELVS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: RABGGTB (Rab Geranylgeranyltransferase, beta Subunit (RABGGTB))

Alternative Name: Rabggtb

Background: Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta),FUNCTION: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A. {ECO:0000269|PubMed:21520375}.

Molecular Weight: 37.8 kDa

UniProt: P53612

AlphaFold: P53612