TBC1D1 Protein (AA 1-1255) (His tag)

Catalog No. ABIN7563888

Recombinant TBC1D1 protein expressed in HEK-293 Cells.

Quick Overview for TBC1D1 Protein (AA 1-1255) (His tag) (ABIN7563888)

Target: TBC1D1 (TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1255

Purification tag / Conjugate: This TBC1D1 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Tbc1d1 Protein expressed in mammalian cells.

Sequence: MEAITFTARK HPFPNEVSVD FGLQLVGSLP VHSLTTMPML PWVVAEVRRL SGQCSKKEPR TKQVRLWVSP SGLRCEPDLE KSQPWDPLIC SSIFECKPQR VHKLIHNSHD PSYFACLIKE DAAHRQSLCY VFKADDQTKV PEIISSIRQA GKIARQEELR CPSEFDDTFA KKFEVLFCGR VTVAHKKAPP ALIDECIEKF NHVSCGRRTD WEAPTGQPSA PGPRPMRKSF SQPGLRSLAF RKEFQDASLR SSTFSSFDND IENHLIGGHN VVQPTDMEEN RTMLFTIGQS EVYLISPDTK KIALEKNFKE ISFCSQGIRH VDHFGFICRE CSGGGSGGFH FVCYVFQCTN EALVDEIMMT LKQAFTVAAV QQTAKAPAQL CEGCPLQGLH KLCERIEGMN SSKTKLELQK HLTTLTNQEQ ATIFEEVQKL RPRNEQRENE LIISFLRCLY EEKQKEHSHT GEPKQTLQVA AENIGSDLPP SASRFRLDSL KNRAKRSLTE SLESILSRGN KARGLQDHSA SVDLDSSTSS TLSNTSKELS MGDKEAFPVS ETSFKLLGSS DDLSSDSEGH IAEESALLSP QQAFRRRANT LSHFPVECPA PPEPAQSSPG VSQRKLMRYH SVSTETPHER NVDHLPGGES QGCPGQPSAP PPPRLNPSAS SPNFFKYLKH NSSGEQSGNA VPKSVSYRNA LRKKLHSSSS VPNFLKFLAP VDENNTCDFK NTNRDFESKA NHLGDTDGTP VKTRRHSWRQ QIFLRVATPQ KACDSPSRYE DYSELGELPP RSPLEPVCED GPFGPVQEEK RKTSRELREL WKKAILQQIL LLRMEKENQK LQASENDLLN KRLKLDYEEI TPCLKEVTTV WEKMLSTPGR SKIKFDMEKV HSAVGQGVPR HHRGEIWKFL AEQFHLKHPF PSKQQPKDVP YKELLKKLTS QQHAILIDLG RTFPTHPYFS AQLGAGQLSL YNILKAYSLL DQEVGYCQGL SFVAGILLLH MSEEEAFKML KFLMFDMGLR KQYRPDMIIL QIQMYQLSRL LHDYHRDLYN HLEEHEIGPS LYAAPWFLTV FASQFPLGFV ARVFDMIFLQ GSEVIFKVAL SLLGSHKPLI LQHENLETIV DFIKNTLPNL GLVQMEKTIS QVFEMDIAKQ LQAYEVEYHV LQEELIESSP LSDNQRMEKL EKTNSSLRKQ NLDLLEQLQV ANARIQSLEA TVEKLLTSES KLKQAALTLE VERSALLQMV EELRRQSARP STPEPDCTQL EPTGD Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TBC1D1 (TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))

Alternative Name: Tbc1d1

Background: TBC1 domain family member 1,FUNCTION: May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells. {ECO:0000269|PubMed:19740738}.

Molecular Weight: 142.0 kDa

UniProt: Q60949

AlphaFold: Q60949