TBC1D17 Protein (AA 1-645) (His tag)

Catalog No. ABIN7564463

This Recombinant TBC1D17 protein is expressed in HEK-293 Cells.

Quick Overview for TBC1D17 Protein (AA 1-645) (His tag) (ABIN7564463)

Target: TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-645

Purification tag / Conjugate: This TBC1D17 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Tbc1d17 Protein expressed in mammalian cells.

Sequence: MEGSSYRVVF EKGGVYLHTS ARKHQDPDSL IAGVIRVVEK DSDVFLHWAP VEEAGDPTQI LFKKDPSRGE PSTSEEEPTF DPGYEPDWAV ISTVRPQPHL AEPRKGAEPS SSRSSWAFSV SLGELKSIRR SKPGLSWAYL VLVTQAGGSL PALHFHRGGT RALLRVLSRY LLLASSPQDS RLYLVFPQDP SALSDSFHHL QLFDQDSSNV VSRFLQDPYS TTFSSFSRVT NFFRGALQPH PEGASSPNLP PLPDDEPEPG FEVISCVELG QRPTVERAPP VTEEEWNRYV GPEGRLQNVP ELKNRIFSGG LSPGLRREAW KFLLGYLSWE SSAEEHKAHV RKKTDEYFRM KLQWKSVSAE QERRNSLLHG YRSLIERDVS RTDRTNKFYE GPENPGLSLL HDILLTYCMY HFDLGYVQGM SDLLSPILFV VQNEVDAFWC FCGFMELVHG NFEESQETMK RQLGQLLLLL RVLDQPLCDF LDSQDSGSLC FCFRWLLIWF KREFPFPDVL RLWEVLWTGL PGPNLHLLVA CAILDMERDT LMLSGFGSNE ILKHINELTM KLSVEDVLTR AEALYRQLTA CPELPHNVQE ILGLAQPEEP SSPSPPVSPM PLSPTRAPLP PPLPEEVIPQ PDSSLEILPE DEDGA Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))

Alternative Name: Tbc1d17

Background: TBC1 domain family member 17,FUNCTION: Probable GTPase-activating protein that inhibits RAB8A/B function. Reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC) and inhibits Rab8-mediated endocytic trafficking, such as that of transferrin receptor (TfR). Involved in regulation of autophagy. {ECO:0000250|UniProtKB:Q9HA65}.

Molecular Weight: 72.9 kDa

UniProt: Q8BYH7

AlphaFold: Q8BYH7