Synaptojanin 2 Protein (SYNJ2) (AA 1-1434) (His tag)

Catalog No. ABIN7564974

Recombinant Synaptojanin 2 protein expressed in HEK-293 Cells.

Quick Overview for Synaptojanin 2 Protein (SYNJ2) (AA 1-1434) (His tag) (ABIN7564974)

Target: Synaptojanin 2 (SYNJ2)

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1434

Purification tag / Conjugate: This Synaptojanin 2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Synj2 Protein expressed in mammalian cells.

Sequence: MALSKGLRLL ARLDPTGPSS VLLEARGRGD CLLFEAGAVA TLAPEEKEVI KGLYSKLTDA YGCLGELRLQ SGGVPLSFLV LVTGCMSVGR IPDAEIYKIT ATELYPLQEE AKEEDRLPTL KKILSSGVFY FAWPNDGACF DLTIRAQKQG DDGSEWGTSF FWNQLLHVPL RQHQVNCHNW LLKVICGVVT IRTVYASHKQ AKACLISRIS CERAGARFLT RGVNDDGHVS NFVETEQTIY MDDGVSSFVQ IRGSVPLFWE QPGLQVGSHH LRLHRGLEAN APAFERHMVL LKEQYGKQVV VNLLGSRGGE EVLNRAFKKL LWASCHAGDT PMINFDFHQF AKGRKLEKLE NLLRPQLQLH WEDFGVFAKG ENVSPRFQKG TLRMNCLDCL DRTNTVQCFI ALEVLHLQLE SLGLNSKPII DRFVESFKAM WSLNGHSLSK VFTGSRALEG KAKVGKLKDG ARSMSRTIQS NFFDGVKQEA IKLLLVGDVY NEESTDKGRM LLDNTALLAT PRILKAMTER QSEFTNFKRI QIAVGTWNVN GGKQFRSNLL GTAELTDWLL DAPQLSGAVD SQDDGSPADV FAIGFEEMVE LSAGNIVNAS TTNRKMWGEQ LQKAISRSHR YILLTSAQLV GVCLYIFVRP YHVPFIRDVA IDTVKTGMGG KAGNKGAVGI RFQLHSTSFC FVCSHLTAGQ SQVKERNEDY REITHKLSFP SGRNIFSHDY VFWCGDFNYR IDLTYEEVFY FVKRQDWKKL MEFDQLQLQK SSGKIFKDFH EGAVNFGPTY KYDVGSAAYD TSDKCRTPAW TDRVLWWRKK HPYDKTAGEL NLLDSDLDGD PQIRHTWSPG TLKYYGRAEL QASDHRPVLA IVEVEVQEVD VGARERVFQE VSSVQGPLDA TVVVNLQSPT LEEKNEFPED LRTELMQTLG NYGTIILVRI NQGQMLVTFA DSHSALSVLD VDGMKVKGRA VKIRPKTKDW LEGLREELLR KRDSMAPVSP TANSCLLEEN FDFSSLDYES EGDVLEEDED YLVDGFGQPV VSDSELGGDN SSDTMSSLTP ASKSPALAKK KQHPTYKAGL MVKKSASDAS ISSGTHGQYS ILQTAKLLPG APQQPPKART GISKPYNVKQ IKTTNAQEAE AAIRCLLEAS GGVPESAPGA IPLRNQGSSK PEATLGPPAL PRRPAPRVPT MKKPTLRRTG KPMLPEENFE PQPVHFTMAS QEMNLETPPP ITATPIPPVP KPRTLQPGKG VEGRPSSGKP EPDEAPSVTG TVESPPPEAQ EAPSLAPKVP PRRKKSAPAA FHLQVLQNNS QVLQGLTCSS SSPPSLKPDT HPLCLQVALG TSSARSPETH GPRVTEPEAA SFHGNYPDPF WSLLHHPKLL NNTWLSKSSE PLDVGSRNPE RTHTEPAQVN ASLAERGLPP DHGGKDLSHW VTASNKDKRT TLGV Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Synaptojanin 2 (SYNJ2)

Alternative Name: Synj2

Background: Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2),FUNCTION: Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis (By similarity). {ECO:0000250, ECO:0000269|PubMed:9442075}.

Molecular Weight: 158.5 kDa

UniProt: Q9D2G5

AlphaFold: Q9D2G5

Pathways: Inositol Metabolic Process