NTSR2 Protein (DYKDDDDK Tag,Strep Tag)
Quick Overview for NTSR2 Protein (DYKDDDDK Tag,Strep Tag) (ABIN7596849)
Target
See all NTSR2 ProteinsProtein Type
Origin
Source
Application
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Purification tag / Conjugate
- This NTSR2 protein is labelled with DYKDDDDK Tag,Strep Tag.
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Purpose
- Human NTR2-Strep full length protein-synthetic nanodisc
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Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- NTSR2 (Neurotensin Receptor 2 (NTSR2))
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Alternative Name
- NTR2
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Background
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NTR2
The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008] -
Molecular Weight
- The human full length NTR2-Strep protein has a MW of 45.4 kDa
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UniProt
- O95665
Target
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