Ketohexokinase (KHK) Protein

Details for Product No. ABIN806523, Supplier: Log in to see
Protein Name
  • wu:fj68h03
  • zgc:92219
  • zgc:92626
  • KHK
  • khk
  • KETHPRO
  • ketohexokinase
  • Ketohexokinase
  • KHK
  • khk
  • Hhal_0921
  • AaeL_AAEL006316
  • Nwat_0240
  • Khk
Origin
Human
12
1
1
Source
Escherichia coli (E. coli)
3
3
2
2
1
1
1
Protein Type
Recombinant
Application
Immunofluorescence (IF), ELISA, Western Blotting (WB)
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Characteristics Ketohexokinase Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 298 AA and having a molecular mass of 32.7 kDa
Purity > 90.0 %
Sterility Sterile filtered
Background Ketohexokinase catalyzes the phosphorylation of fructose to produce fructose-1-phosphate, resulting in the utilization of ATP and creation of AMP. Ketohexokinase commences initial step in the metabolism of dietary fructose and is a significant regulator of hepatic glucose metabolism. Ketohexokinase is found in liver, renal cortex, and small intestine. Its deficiency causes the benign hereditary metabolic disorder essential fructosuria, leading to fructose being excreted in the urine. Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells. ketohexokinase plays an unknown physiologic function that remains intact in essential fructosuria. Ketohexokinase expression is reduceed in human clear cell type of renal cell carcinoma

Synonyms: KHK, Hepatic Fructokinase, Ketohexokinase, Fructokinase
Molecular Weight 44.4 kDa
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer The protein solution contains 1xPBS, pH 7.4 and 10 % glycerol.
Handling Advice Please avoid freeze thaw cycles.
Storage 4 °C