DEFB4A Protein

Catalog No. ABIN871817

Product Details

Target: DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM

Purity: > 97 % by SDS-PAGE and HPLC analyses.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 1EU/µg of rRtSDF-1beta/CXCL12 as determined by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20° C. Further dilutions should be made in appropriate buffered solutions.

Storage: 4 °C/-20 °C

Target Details

Target: DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

Alternative Name: BD-2 (DEFB4 Products)

Synonyms: BD-2 Protein, DEFB-2 Protein, DEFB102 Protein, DEFB2 Protein, DEFB4 Protein, HBD-2 Protein, SAP1 Protein, BD2 Protein, DEFB4P Protein, THP2 Protein, defensin beta 4A Protein, defensin beta 2 Protein, defensin beta 1 Protein, avian beta-defensin 4 Protein, defensin, beta 4A Protein, beta-defensin 2 Protein, defensin beta 4 Protein, beta defensin 2 Protein, DEFB4A Protein, Defb2 Protein, DEFB1 Protein, AvBD4 Protein, THP2 Protein, defb4 Protein, SBD2 Protein

Background: SDF-1alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.