Defensin beta 3 Protein (DEFB3)

Catalog No. ABIN871818

Product Details

Target: Defensin beta 3 (DEFB3)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM

Purity: > 97 % by SDS-PAGE and HPLC analyses.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 1EU/µg of rRtSDF-1beta/CXCL12 as determined by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20° C. Further dilutions should be made in appropriate buffered solutions.

Storage: 4 °C/-20 °C

Target Details

Target: Defensin beta 3 (DEFB3)

Alternative Name: BD-3 (DEFB3 Products)

Synonyms: BD-3 Protein, DEFB-3 Protein, DEFB103 Protein, DEFB3 Protein, HBD3 Protein, HBP-3 Protein, HBP3 Protein, hBD-3 Protein, BNBD-3 Protein, BNBD-6 Protein, BNDB-3 Protein, BNDB-6 Protein, BNDB3 Protein, DEFB103A Protein, DEFB2 Protein, DEFB6 Protein, bnbd3 Protein, defb405 Protein, defensin beta 103A Protein, defensin beta 3 Protein, beta-defensin 3 Protein, DEFB103A Protein, Defb3 Protein, DEFB3 Protein

Background: SDF-1alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.

Pathways: Production of Molecular Mediator of Immune Response