Annexin a1 Protein (AA 1-346)

Catalog No. ABIN935028

Product Details

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Protein Type: Recombinant

Protein Characteristics: AA 1-346

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MAMVSEFLKQ AWFIENEEQE YVQTVKSSKG GPGSAVSPYP TFNPSSDVAA LHKAIMVKGV DEATIIDILT KRNNAQRQQI KAAYLQETGK PLDETLKKAL TGHLEEVVLA LLKTPAQFDA DELRAAMKGL GTDEDTLIEI LASRTNKEIR DINRVYREEL KRDLAKDITS DTSGDFRNAL LSLAKGDRSE DFGVNEDLAD SDARALYEAG ERRKGTDVNV FNTILTTRSY PQLRRVFQKY TKYSKHDMNK VLDLELKGDI EKCLTAIVKC ATSKPAFFAE KLHQAMKGVG TRHKALIRIM VSRSEIDMND IKAFYQKMYG ISLCQAILDE TKGDYEKILV ALCGGN

Characteristics: Purified recombinant Human Annexin A1 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Purity: > 90 % pure

Application Details

Application Notes: Annexin A1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 100 mM NaCl, 0 mM DTT, and 10 % glycerol.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: Annexin A1 (ANXA1 Products)

Synonyms: anx1a Protein, anxa1 Protein, wu:fa01d11 Protein, wu:fa05d11 Protein, wu:fk69h01 Protein, MGC64363 Protein, anx1 Protein, lpc1 Protein, MGC89164 Protein, ANXA1 Protein, ANX1 Protein, LPC1 Protein, p35 Protein, Anx-1 Protein, Anx-A1 Protein, C430014K04Rik Protein, Lpc-1 Protein, Lpc1 Protein, Anx1 Protein, annexin A1a Protein, annexin A1 Protein, annexin A1 L homeolog Protein, Annexin A1 Protein, anxa1a Protein, anxa1 Protein, anxa1.L Protein, ANXA1 Protein, LOC100335033 Protein, Anxa1 Protein

Target Type: Chemical

Background: Annexin A1, also known as Lipocortin I, belongs to a family of Ca(2+)-dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. It promotes membrane fusion and is also involved in exocytosis. Since Annexin A1 has phospholipase A2 inhibitory activity to bind from two to four calcium ions with high affinity, this protein may have potential anti-inflammatory activity. The detection of this protein by immunocytochemical means reportedly provides a simple, highly sensitive and specific assay for diagnosis of hairy cell leukemia. Recombinant human Annexin A1 protein was expressed in E. coli and purified by using conventional chromatography.
Alternative Names: Annexin A-1, AnnexinI protein, Chromobindin9 protein, Chromobindin-9 protein, Lipocortin I protein, Phospholipase A2 inhibitory protein protein, HGNC:533 protein, Annexin I protein, Lipocortin 1 protein, Annexin A 1, ANXA 1 protein, Calpactin II protein, CalpactinII protein, p35 protein, , AnnexinA1 protein, Annexin A1, LipocortinI protein, Lipocortin1 protein, ANX1 protein, LPC 1 protein, ANX 1 protein, Lipocortin I protein, ANX A1 protein, Annexin A 1 protein, ANXA1 protein, Chromobindin 9 protein, ANXA1 protein protein, LPC1 protein, Annexin-1 protein, Annexin A-1 protein

Molecular Weight: 38.7 kDa (346 AA)

Pathways: Hormone Transport