FGF19 Protein
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- Target See all FGF19 Proteins
- FGF19 (Fibroblast Growth Factor 19 (FGF19))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
- Characteristics
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Purified recombinant Human FGF19 protein
Expression System: E.coli
Bioactivity: Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 100-150 ng/mL. - Purity
- > 95 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product FGF19 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- Lyophilized from 5 mM Tris, pH 7.6, with 75 mM NaCl.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development." in: Neural development, Vol. 3, pp. 17, (2008) (PubMed).
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FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development." in: Neural development, Vol. 3, pp. 17, (2008) (PubMed).
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- Target
- FGF19 (Fibroblast Growth Factor 19 (FGF19))
- Alternative Name
- FGF19 (FGF19 Products)
- Synonyms
- FGF-19 Protein, Fgf15 Protein, fibroblast growth factor 19 Protein, FGF19 Protein, Fgf19 Protein, fgf19 Protein
- Background
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The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF19, a member of the FGF family, is a high affinity heparin dependent ligand for FGFR4. FGF19 is expressed during the brain development and embryogenesis.
Alternative Names: FGF 19 protein, FGF19, FGFJ protein, FGF-19, FGF 19, Fibroblast Growth Factor-19 protein, FGF-19 protein, FGF-19 protein - Molecular Weight
- 21.8 kDa
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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