Allopregnanolone Protein

Details for Product No. ABIN93543
Protein Name
Origin
Hormone
Host
Application
Radioimmunoassay (RIA)
Options
Characteristics produced by Umecrine AB
Purification affinity purified
Protein Name
Background Allopregnanolone, (3alpha-hydroxy-20-oxo-5alphapregnan-11alpha-yl-carboxymethylether), also known as 3alpha,5alpha-tetrahydroprogesterone or THP, a neuroactive steroid secreted by the mammalian ovary, exerts its anesthetic, anxiolytic, and sedative/hypnotic effects through potentiation of GABA A receptors. It is produced in the human corpus luteum and their release is stimulated by trophic hormone.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Buffer 0
Handling Advice Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Once reconstituted make aliquots to avoid repreated freeze-thaw cycles.
Storage -20 °C
Storage Comment store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Product cited in: Mayes, Bossini-Castillo, Gorlova, Martin, Zhou, Chen, Assassi, Ying, Tan, Arnett, Reveille, Guerra, Teruel, Carmona, Gregersen, Lee, López-Isac, Ochoa, Carreira, Simeón, Castellví, González-Gay et al.: "Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. ..." in: American journal of human genetics, Vol. 94, Issue 1, pp. 47-61, 2014 (PubMed).