TWSG1 Protein
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- Target See all TWSG1 Proteins
- TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- MCNKALCASD VSKCLIQELC QCRPGEGNCS CCKECMLCLG ALWDECCDCV GMCNPRNYSD TPPTSKSTVE ELHEPIPSLF RALTEGDTQL NWNIVSFPVA EELSHHENLV SFLETVNQPH HQNVSVPSNN VHAPYSSDKE HMCTVVYFDD CMSIHQCKIS CESMGASKYR WFHNACCECI GPECIDYGSK TVKCMNCMF
- Characteristics
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Purified recombinant Human TSG protein
Expression System: E.coli
Bioactivity: Determined by its ability to neutralize BMP-6 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product TWSG1 Protein
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Twisted Gastrulation Homolog 1 (TWSG1) (AA 1-223) protein (GST tag)
TWSG1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Twisted Gastrulation Homolog 1 (TWSG1) (AA 124-223) protein (GST tag)TWSG1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Twisted Gastrulation Homolog 1 (TWSG1) protein (His tag)TWSG1 Origin: Mouse Host: HEK-293 Cells Recombinant > 93 % as determined by SDS-PAGE
Twisted Gastrulation Homolog 1 (TWSG1) (AA 26-223) protein (His tag)Crystallography grade TWSG1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))
- Alternative Name
- TSG (TWSG1 Products)
- Background
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Twisted Gastrulation Protein (TSG) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex.
Alternative Names: Twisted Gastrulation Protein protein - Molecular Weight
- 22.2 kDa
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