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CCL24 Protein

CCL24 Origin: Human Host: Escherichia coli (E. coli) > 97 % by SDS-PAGE and HPLC analyses. Active
Catalog No. ABIN987809
  • Target See all CCL24 Proteins
    CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
    Biological Activity
    Active
    Origin
    • 10
    • 7
    • 4
    • 2
    Human
    Source
    • 13
    • 6
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAV
    Characteristics
    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood eosinophils is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.
    Purity
    > 97 % by SDS-PAGE and HPLC analyses.
    Endotoxin Level
    Level Less than 1EU/µg of rHuEotaxin-2/CCL24 as determined by LAL method
    Top Product
    Discover our top product CCL24 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    Storage
    4 °C
  • Target
    CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
    Alternative Name
    Eotaxin-2/CCL24 (CCL24 Products)
    Synonyms
    Ckb-6 Protein, MPIF-2 Protein, MPIF2 Protein, SCYA24 Protein, CKb-6 Protein, Scya24 Protein, C-C motif chemokine ligand 24 Protein, chemokine (C-C motif) ligand 24 Protein, CCL24 Protein, Ccl24 Protein
    Background
    Eotaxin, also named MPIF-2 and Ckbeta6, is a novel CC chemokine recently identified. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the mouse homolog, without C-terminal truncation). Synonym: Eotaxin-2/CCL24, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
    Molecular Weight
    8.8 kDa, a single non-glycosylated polypeptide chain containing 78 amino acids.
    Pathways
    Regulation of Actin Filament Polymerization
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