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CCL21 Protein

CCL21 Origin: Mouse Host: Escherichia coli (E. coli) > 97 % by SDS-PAGE and HPLC analyses. Active
Catalog No. ABIN987840
  • Target See all CCL21 Proteins
    CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
    Biological Activity
    Active
    Origin
    • 12
    • 6
    • 2
    • 1
    • 1
    Mouse
    Source
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSR
    Characteristics
    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood lymphocytes is less than 200 ng/ml, corresponding to a specific activity of >, 5.0 × 103 IU/mg.
    Purity
    > 97 % by SDS-PAGE and HPLC analyses.
    Endotoxin Level
    Level Less than 1EU/µg of rMuExodus-2/CCL21 as determined by LAL method
    Top Product
    Discover our top product CCL21 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    Storage
    4 °C
  • Target
    CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
    Alternative Name
    Exodus-2/CCL21 (CCL21 Products)
    Synonyms
    6Ckine Protein, CKb9 Protein, ECL Protein, SCYA21 Protein, SLC Protein, TCA4 Protein, ccl21 Protein, Ccl21b Protein, C-C motif chemokine ligand 21 Protein, C-C motif chemokine 21 Protein, CCL21 Protein, ccl21 Protein, Ccl21 Protein
    Background
    Exodus-2/CCL21 is a novel CC chemokine discovered independently by three groups from the EST database, and shows 21-33% identity to other CC chemokines. Exodus-2 contains the four conserved cysteines characteristic of beta chemokines plus two additional cysteines in its unusually long carboxylterminal domain. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Synonym: Exodus-2/CCL21, Mouse. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
    Molecular Weight
    12.0 kDa, a single, non-glycosylated polypeptide chain containing 110 amino acids.
    Pathways
    Regulation of Actin Filament Polymerization
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