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CCL7 Protein

CCL7 Origin: Human Host: Escherichia coli (E. coli) > 97 % by SDS-PAGE and HPLC analyses. Active
Catalog No. ABIN988136
  • Target See all CCL7 Proteins
    CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
    Biological Activity
    Active
    Origin
    • 10
    • 6
    • 4
    Human
    Source
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPK
    Characteristics
    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 80 ng/ml, corresponding to a specific activity of >, 1.3 × 104 IU/mg.
    Purity
    > 97 % by SDS-PAGE and HPLC analyses.
    Endotoxin Level
    Level Less than 1EU/µg of rHuMCP-3/CCL7 as determined by LAL method
    Top Product
    Discover our top product CCL7 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    Storage
    4 °C
  • Target
    CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
    Alternative Name
    MCP-3/CCL7 (CCL7 Products)
    Synonyms
    CCL7 Protein, FIC Protein, MARC Protein, MCP-3 Protein, MCP3 Protein, NC28 Protein, SCYA6 Protein, SCYA7 Protein, Scya7 Protein, fic Protein, marc Protein, mcp3 Protein, C-C motif chemokine ligand 7 Protein, chemokine (C-C motif) ligand 7 Protein, CCL7 Protein, Ccl7 Protein
    Background
    MCP2 and CCL7 are two monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP2 and CCL7 are members of the CC family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. CCL7 also shares 58% amino acid identity with MCP2.Similarly to other CC chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils. Synonym: MCP-3/CCL7, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4,150mM NaCl.
    Molecular Weight
    9.0 kDa, a single, non-glycosylated polypeptide chain containing 76 amino acids.
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