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Human Polyclonal ATP5H Primary Antibody for IHC, WB - ABIN6713482
Wang, Chen, Li, Zhang, Jia, Li, Chi, Miao, Guan, Yang: Hepatic overexpression of ATP synthase β subunit activates PI3K/Akt pathway to ameliorate hyperglycemia of diabetic mice. in Diabetes 2014
multimodality resistance arises through a core metabolic reprogramming pathway instigated by epigenetic loss of the ATP synthase subunit ATP5H, which leads to ROS accumulation and HIF-1alpha stabilization under normoxia
ATP5H loss in the tumor is strongly linked to failure of therapy, disease progression, and poor survival in patients with cancer.
The Network analyses identified ATP5H expression in temporal cortex in patient with late-onset Alzheimer's disease.
By merging results of a meta-GWAS, results in the CHARGE consortium data sets and an in vivo genotyping comprising 4501 individuals, detected a novel locus ATP5H/KCTD2 associated with Alzheimer's disease risk
This protein has been found differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15.
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d
, ATP synthase subunit d, mitochondrial
, ATPase subunit d
, ATP synthase D chain, mitochondrial
, ATP synthase, H+ transporting, mitochondrial F1F0, subunit d
, My032 protein