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|Antigen||Chemokine (C-C Motif) Receptor 7 (CCR7) Antibodies|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This CCR7 antibody is un-conjugated Alternatives|
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
|5 references available|
|Supplier||Log in to see|
Product Details anti-CCR7 AntibodyTarget Details CCR7 Application Details Handling References for anti-CCR7 antibody (ABIN4900691) Images
|Specificity||Detects mouse CCR7.|
|Purification||Protein A or G purified from hybridoma culture supernatant|
|Sterility||0.2 μm filtered|
|Endotoxin Level||<0.10 EU per 1 μg of the antibody by the LAL method.|
|Immunogen||RBC-2H3 cells expressing mouse CCR7, Accession # NP_031745|
|Plasmids, Primers & others|
Target Details CCR7Product Details anti-CCR7 Antibody Application Details Handling References for anti-CCR7 antibody (ABIN4900691) Images back to top
|Alternative Name||CCR7 (CCR7 Antibody Abstract)|
|Background||Alternative Names: BLR2C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR7, CCR-7, CD197, CD197 antigen, CDw197CC chemokine receptor 7, chemokine (C-C motif) receptor 7, CMKBR7chemokine (C-C) receptor 7, EBI1EBV-induced G protein-coupled receptor 1, EBV-induced G-protein coupled receptor 1, Epstein-Barr virus induced gene 1, Epstein-Barr virus induced G-protein coupled receptor, Epstein-Barr virus-induced G-protein coupled receptor 1, EVI1, lymphocyte-specific G protein-coupled peptide receptor, MIP-3 beta receptor|
|Pathways||Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process|
Application DetailsProduct Details anti-CCR7 Antibody Target Details CCR7 Handling References for anti-CCR7 antibody (ABIN4900691) Images back to top
Flow Cytometry 0.25 μg/10^6 cells
Neutralization 2-10 μg/mL
Immunocytochemistry 8-25 μg/mL
|Restrictions||For Research Use only|
HandlingProduct Details anti-CCR7 Antibody Target Details CCR7 Application Details References for anti-CCR7 antibody (ABIN4900691) Images back to top
|Reconstitution||Reconstitute at 0.5 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-CCR7 antibody (ABIN4900691)Product Details anti-CCR7 Antibody Target Details CCR7 Application Details Handling Images back to top
|Product cited in:||
Dong, Wang, Xiao, Pacios Pujado, Xu, Tian, Xiao, Choi, Graves: "FOXO1 regulates dendritic cell activity through ICAM-1 and CCR7." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3745-55, 2015 Method employed by authors: Immunofluorescence (IF), Immunofluorescence (IF), Immunofluorescence (IF) (Sample species: Mouse (Murine)).
Pang, Georgoudaki, Lambut, Johansson, Tabor, Hagikura, Jin, Jansson, Alexander, Nelson, Jakobsson, Betsholtz, Sund, Karlsson, Fuxe: "TGF-?1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis." in: Oncogene, 2015
Irino, Takeuchi, Matsuda, Saikawa, Kawakubo, Wada, Takahashi, Nakamura, Fukuda, Omori, Kitagawa: "CC-Chemokine receptor CCR7: a key molecule for lymph node metastasis in esophageal squamous cell carcinoma." in: BMC cancer, Vol. 14, pp. 291, 2014 Method employed by authors: ELISA (ELISA), ELISA (ELISA), ELISA (ELISA) (Sample species: Human).
Ibrahim, Barnes, Osorio, Anstead, Jimenez, Osterholzer, Travi, Ahuja, White, Melby: "Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection." in: Infection and immunity, Vol. 82, Issue 8, pp. 3098-112, 2014 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Mouse (Murine)).
Wan, Zhou, Duan, Morel: "Direct B cell stimulation by dendritic cells in a mouse model of lupus." in: Arthritis and rheumatism, Vol. 58, Issue 6, pp. 1741-50, 2008 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Mouse (Murine)).
ImagesProduct Details anti-CCR7 Antibody Target Details CCR7 Application Details Handling References for anti-CCR7 antibody (ABIN4900691) back to top