anti-Human Carboxypeptidase B2 (Plasma) antibody for Enzyme Immunoassay

Recommended Carboxypeptidase B2 (Plasma) Antibody (supplied by: Log in to see )

Antigen
Carboxypeptidase B2 (Plasma) (CPB2) Antibodies
  • CPU
  • PCPB
  • TAFI
  • 1700120C01Rik
  • AI325129
  • CPB1
  • CPB2
  • CPbeat2
  • CPbeta1
  • CPbeta2
  • Cappb1
  • 1110032P04Rik
  • 4930405E17Rik
  • AI255929
  • CPR
  • Cpu
  • pCPB
  • zgc:112493
  • carboxypeptidase B2
  • capping protein (actin filament) muscle Z-line, beta
  • carboxypeptidase B2 (plasma)
  • CPB2
  • Capzb
  • Cpb2
  • cpb2
Epitope
AA 126-156
11
5
5
5
5
5
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
154
42
25
2
1
1
1
1
1
Host
Rabbit
83
82
16
Clonality
Polyclonal
Conjugate
Un-conjugated
10
9
8
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
121
118
17
13
9
6
5
5
3
3
3
2
2
2
1
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Catalog No. ABIN452866
$ 390.50
Plus shipping costs $45.00

General

Antigen Carboxypeptidase B2 (Plasma) (CPB2) Antibodies
Epitope AA 126-156
(11), (5), (5), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(154), (42), (25), (2), (1), (1), (1), (1), (1)
Host Rabbit
(83), (82), (16)
Clonality
Polyclonal
Conjugate Un-conjugated
(10), (9), (8), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(121), (118), (17), (13), (9), (6), (5), (5), (3), (3), (3), (2), (2), (2), (1)
Pubmed 1 reference available
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Product details

Target Details Application Details Handling References Images
Specificity This antibody detects CPB2 (aa 126~156).
Cross-Reactivity (Details) Species reactivity (tested):Human,
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen KLH conjugated synthetic peptide selected between 126~156 amino acids from the Center region of Human CPB2

Target Details

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Antigen
Alternative Name Carboxypeptidase B2 (CPB2 Antibody Abstract)
Background Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.Synonyms: CPB2, CPU, Carboxypeptidase U, Plasma carboxypeptidase B, TAFI, Thrombin-activable fibrinolysis inhibitor, pCPB
Molecular Weight 48412 Da
Gene ID 1361
NCBI Accession NP_001863
UniProt Q96IY4
Pathways Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis

Application Details

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Application Notes ELISA: 1/1,000. Western blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product details Target Details Application Details References Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References

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Background publications

Valnickova, Thogersen, Christensen, Chu, Pizzo, Enghild: "Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein." in: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12937-43, 1996

Images

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Supplier Images
 image for anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 126-156) antibody (ABIN452866) anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 126-156) antibody