anti-Human Discs, Large Homolog 1 (Drosophila) antibody for Immunohistochemistry

Recommended Discs, Large Homolog 1 (Drosophila) Antibody (supplied by: Log in to see )

Antigen
Discs, Large Homolog 1 (Drosophila) (DLG1) Antibodies
  • DLG1
  • Dlgh1
  • SAP97
  • B130052P05Rik
  • E-dlg/SAP97
  • SAP-97
  • mKIAA4187
  • DLGH1
  • dJ1061C18.1.1
  • hdlg
  • discs large MAGUK scaffold protein 1
  • discs, large homolog 1 (Drosophila)
  • DLG1
  • Dlg1
Epitope
AA 2-50
10
5
4
4
3
3
2
2
2
1
1
1
1
Reactivity
Human, Rat (Rattus), Mouse (Murine)
42
23
19
2
2
2
2
1
1
1
1
1
1
1
Host
Rabbit
20
16
16
1
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
51
21
14
9
7
4
4
4
2
2
1
1
1
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Available images

Catalog No. ABIN571847
$ 454.67
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.120859 ABIN4903485 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN4305323 ICC IF IHC IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see S64-15 6
1 ABIN269417 ICC IF IHC IHC (fro) IP WB Rabbit IgG Log in to see Polyclonal 4
1 ABIN5661671 IHC WB Rabbit Log in to see Polyclonal 0

General

Antigen Discs, Large Homolog 1 (Drosophila) (DLG1) Antibodies
Epitope AA 2-50
(10), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus), Mouse (Murine)
(42), (23), (19), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(20), (16), (16), (1)
Clonality
Polyclonal
Conjugate Un-conjugated
(1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(51), (21), (14), (9), (7), (4), (4), (4), (2), (2), (1), (1), (1)
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Product details

Target Details Application Details Handling Images
Specificity Specific for SAP97.
Purification Whole serum
Immunogen A synthetic peptide from aa region 2-50 of human SAP97 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Target Details

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Antigen
Alternative Name SAP97 (DLG1 Antibody Abstract)
Background Function: Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel.
Subcellular location: Membrane, Peripheral membrane protein. Basolateral cell membrane. Endoplasmic reticulum membrane. Cell junction › synapse › postsynaptic cell membrane › postsynaptic density. Cell junction › synapse. Cell membrane › sarcolemma. Note: Colocalizes with EPB41 at regions of intercellular contacts. Basolateral in epithelial cells. May also associate with endoplasmic reticulum membranes. Mainly found in neurons soma, moderately found at postsynaptic densities.
Tissue specificity: Abundantly expressed in atrial myocardium (at protein level). Expressed in lung fibroblasts, cervical epithelial and B-cells (at protein level). Widely expressed, with isoforms displaying different expression profiles. Also known as: DLG1, Disks large homolog 1, Synapse-associated protein 97.
Pathways Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response

Application Details

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Application Notes A dilution of 1: 200 to 1: 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only

Handling

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Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months

Images

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Supplier Images
Immunohistochemistry (IHC) image for anti-Discs, Large Homolog 1 (Drosophila) (DLG1) (AA 2-50) antibody (ABIN571847) IHC on paraffin sections of rat brain tissue using Rabbit antibody to SAP97 (2-50): ....
Immunohistochemistry (IHC) image for anti-Discs, Large Homolog 1 (Drosophila) (DLG1) (AA 2-50) antibody (ABIN571847) IHC on paraffin sections of rat heart tissue using Rabbit antibody to SAP97 (2-50): ....
Immunohistochemistry (IHC) image for anti-Discs, Large Homolog 1 (Drosophila) (DLG1) (AA 2-50) antibody (ABIN571847) IHC on paraffin sections of rat kidney tissue using Rabbit antibody to SAP97 (2-50): ...
Immunohistochemistry (IHC) image for anti-Discs, Large Homolog 1 (Drosophila) (DLG1) (AA 2-50) antibody (ABIN571847) IHC on paraffin sections of rat lung tissue using Rabbit antibody to SAP97 (2-50): .H...
Immunohistochemistry (IHC) image for anti-Discs, Large Homolog 1 (Drosophila) (DLG1) (AA 2-50) antibody (ABIN571847) IHC on paraffin sections of rat lung tissue using Rabbit antibody to SAP97 (2-50): .H...