anti-Cat (Feline) Netrin 1 antibody for Western Blotting

Recommended Netrin 1 Antibody (supplied by: Log in to see )

Antigen
Netrin 1 (NTN1) Antibodies
  • ntn1-A
  • Netrin-1
  • NTN1
  • unc-6
  • MGC147073
  • NTN1L
  • AI561871
  • BC019633
  • netrin-1
  • netrin 1 L homeolog
  • netrin 1
  • ntn1.L
  • NTN1
  • ntn1
  • Ntn1
Reactivity
Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Macaque, Cat (Feline)
87
73
54
10
9
5
4
3
3
2
2
1
1
Host
Rabbit
73
14
11
5
4
2
1
Clonality
Polyclonal
Conjugate
This Netrin 1 antibody is un-conjugated
5
5
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
77
41
35
16
13
10
8
7
4
3
3
2
Options
Supplier
Log in to see
Supplier Product No.
Log in to see

Available images

Catalog No. ABIN307033
$ 279.40
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4 ABIN265183 WB Rabbit IgG Log in to see Polyclonal 0
4 ABIN265184 WB Rabbit IgG Log in to see Polyclonal 0
4 ABIN212236 WB Rabbit Log in to see Polyclonal 0
4 ABIN201815 WB Rabbit Log in to see Polyclonal 0

General

Antigen Netrin 1 (NTN1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Macaque, Cat (Feline)
(87), (73), (54), (10), (9), (5), (4), (3), (3), (2), (2), (1), (1)
Host Rabbit
(73), (14), (11), (5), (4), (2), (1)
Clonality
Polyclonal
Conjugate This Netrin 1 antibody is un-conjugated
(5), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(77), (41), (35), (16), (13), (10), (8), (7), (4), (3), (3), (2)
Pubmed 7 references available
Supplier Log in to see

Product Details anti-Netrin 1 Antibody

Target Details Netrin 1 Application Details Handling References for anti-Netrin 1 antibody (ABIN307033) Images
Isotype IgG
Plasmids, Primers & others

Target Details Netrin 1

Product Details anti-Netrin 1 Antibody Application Details Handling References for anti-Netrin 1 antibody (ABIN307033) Images back to top
Antigen
Alternative Name Netrin 1 (NTN1 Antibody Abstract)
Background Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis. Netrin 1's main receptor is DCC (deleted in colorectal cancer- a putative tumor suppressor gene whose expression is lost in numerous cancers). DCC belongs to the so-called family of dependence receptors. These receptors induce apoptosis when their ligand is absent, thus conferring a state of cellular dependence on Netrin 1 availability. The DCC/netrin-1 duo regulates neuron survival during nervous system development. The mechanism(s) by which Netrin 1/ DCC triggers cell death are still unknown. The localization of DCC to lipid rafts appears to be a prerequisite for its proapoptotic activity. Synonyms: Netrin 1, NTN1.
NCBI Accession NP_004813
Pathways Regulation of Cell Size

Application Details

Product Details anti-Netrin 1 Antibody Target Details Netrin 1 Handling References for anti-Netrin 1 antibody (ABIN307033) Images back to top
Application Notes Antibody can be used for Western blotting (0.5-2 ug/ml). Positive Control: Antibody tested on MDCKII cell lysates..
Restrictions For Research Use only

Handling

Product Details anti-Netrin 1 Antibody Target Details Netrin 1 Application Details References for anti-Netrin 1 antibody (ABIN307033) Images back to top
Concentration 1 mg/ml
Storage -20 °C

References for anti-Netrin 1 antibody (ABIN307033)

Product Details anti-Netrin 1 Antibody Target Details Netrin 1 Application Details Handling Images back to top
Background publications

Nguyen, Cai: "Netrin-1 induces angiogenesis via a DCC-dependent ERK1/2-eNOS feed-forward mechanism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 17, pp. 6530-5, 2006

Furne, Corset, Hérincs, Cahuzac, Hueber, Mehlen: "The dependence receptor DCC requires lipid raft localization for cell death signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 11, pp. 4128-33, 2006

Furne, Mehlen: "[The deadly rafts: when lipid rafts regulate dependence receptors]." in: Médecine sciences : M/S, Vol. 22, Issue 11, pp. 909-10, 2006

Nakamura, Takei, Goshima: "[Signaling mechanism connecting axon guidance molecules and growth cone cytoskeleton]." in: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Vol. 51, Issue 6 Suppl, pp. 733-41, 2006

Chang, Adler, Krause, Clark, Gertler, Tessier-Lavigne, Bargmann: "MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin." in: Current biology : CB, Vol. 16, Issue 9, pp. 854-62, 2006

Xie, Hong, Ma, Ren, Ackerman, Mei, Xiong: "DCC-dependent phospholipase C signaling in netrin-1-induced neurite elongation." in: The Journal of biological chemistry, Vol. 281, Issue 5, pp. 2605-11, 2006

Shekarabi, Moore, Tritsch, Morris, Bouchard, Kennedy: "Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, Issue 12, pp. 3132-41, 2005

Images

Product Details anti-Netrin 1 Antibody Target Details Netrin 1 Application Details Handling References for anti-Netrin 1 antibody (ABIN307033) back to top
Supplier Images
Western Blotting (WB) image for anti-Netrin 1 (NTN1) antibody (ABIN307033) Ship at ambient temperature, freeze upon arrival Product should be stored at -20ºC....