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|Antigen||rho Family GTPase 2 (RND2) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This RND2 antibody is conjugated to Alexa Fluor 350 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
|Supplier||Log in to see|
Product Details anti-RND2 AntibodyTarget Details RND2 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human RND2|
Target Details RND2Product Details anti-RND2 Antibody Application Details Handling Images back to top
|Alternative Name||Rnd2/Rho7 (RND2 Antibody Abstract)|
The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50 % amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30 % homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine, A, aliphatic amino acid, X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.
Synonyms: ARHN, Rho 7, Rho family GTPase 2, Rho N, Rho related GTP-binding protein RhoN, Rho-related GTP-binding protein Rho7, Rho-related GTP-binding protein RhoN, Rho7, RhoN, Rnd 2, Rnd2, RND2_HUMAN.
|Pathways||Regulation of Cell Size|
Application DetailsProduct Details anti-RND2 Antibody Target Details RND2 Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-RND2 Antibody Target Details RND2 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|