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|Antigen||Slit Homolog 1 (Drosophila) (SLIT1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This SLIT1 antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-SLIT1 AntibodyTarget Details SLIT1 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human Slit1/MEGF4|
|Plasmids, Primers & others|
Target Details SLIT1Product Details anti-SLIT1 Antibody Application Details Handling Images back to top
|Alternative Name||Slit1/Megf4 (SLIT1 Antibody Abstract)|
Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo) (1, 2). Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs (3,4). Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation (5). Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs (6,7).
Synonyms: MEGF 4, MEGF4, Multiple EGF like domains protein 4, Multiple epidermal growth factor like domains 4, Multiple epidermal growth factor like domains protein 4, SLIL 1, SLIL1, Slit 1, SLIT 3, Slit homolog 1, Slit homolog 1 protein, Slit-1, Slit1, SLIT3, KIAA0813, SLIT1_HUMAN.
|Pathways||Regulation of Cell Size|
Application DetailsProduct Details anti-SLIT1 Antibody Target Details SLIT1 Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-SLIT1 Antibody Target Details SLIT1 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
ImagesProduct Details anti-SLIT1 Antibody Target Details SLIT1 Application Details Handling back to top