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|Antigen||Bone Morphogenetic Protein 5 (BMP5) Antibodies|
|Epitope||AA 332-365, C-Term Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This BMP5 antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
|1 reference available|
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Product Details anti-BMP5 AntibodyTarget Details BMP5 Application Details Handling References for anti-BMP5 antibody (ABIN3043800) Images
|Purpose||Rabbit IgG polyclonal antibody for Bone morphogenetic protein 5(BMP5) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.|
|Sequence||HQDSSRMSSV GDYNTSEQKQ ACKKHELYVS FRDL|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Bone morphogenetic protein 5(BMP5) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.
Gene Name: bone morphogenetic protein 5
Protein Name: Bone morphogenetic protein 5
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of human BMP-5 (332-365aa HQDSSRMSSVGDYNTSEQKQACKKHELYVSFRDL), different from the related mouse sequence by three amino acids.|
|Plasmids, Primers & others|
Target Details BMP5Product Details anti-BMP5 Antibody Application Details Handling References for anti-BMP5 antibody (ABIN3043800) Images back to top
|Alternative Name||BMP5 (BMP5 Antibody Abstract)|
Bone morphogenetic protein 5 is a protein that in humans is encoded by the BMP5 gene. This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. And this protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.
Synonyms: BMP 5 antibody|BMP-5 antibody|Bmp5 antibody|BMP5_HUMAN antibody|Bone morphogenetic protein 5 antibody|MGC34244 antibody
|Pathways||Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process|
Application DetailsProduct Details anti-BMP5 Antibody Target Details BMP5 Handling References for anti-BMP5 antibody (ABIN3043800) Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
|Restrictions||For Research Use only|
HandlingProduct Details anti-BMP5 Antibody Target Details BMP5 Application Details References for anti-BMP5 antibody (ABIN3043800) Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
References for anti-BMP5 antibody (ABIN3043800)Product Details anti-BMP5 Antibody Target Details BMP5 Application Details Handling Images back to top
|Product cited in:||
Wang, Xue, Zhao, Liu, Ma, Ma: "Form-deprivation myopia induces decreased expression of bone morphogenetic protein-2, 5 in guinea pig sclera." in: International journal of ophthalmology, Vol. 8, Issue 1, pp. 39-45, 2015
ImagesProduct Details anti-BMP5 Antibody Target Details BMP5 Application Details Handling References for anti-BMP5 antibody (ABIN3043800) back to top